- Opening a company file
- Running Reports
- Backing up
- Verifying/Rebuilding Company File
The C=224 error indicates that there is a transaction that is corrupt.
Perform a new Verify and Rebuild Data from withing QuickBooks -- instructions are here:
A quick workaround can be to hit "save and new" instead of just "save". No error will appear and normally you can go right back to the invoice.
See this Intuit support article for more information: